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Clinical practice guidelines in cancer treatment

Chemotherapy-induced complications

Recently, both the European Organisation for Research and Treatment of Cancer (EORTC) and the Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) updated important clinical guidelines in the treatment of chemotherapy-associated complications, such as anaemia, neutropenia and oral mucositis.

To aid nurses in their understanding of these new guidelines, EONS has developed this comprehensive Guidelines Implementation Toolkit. The toolkit aims to provide a practical guide to understanding and implementing the new guidelines in day-to-day clinical practice.

Extravasation

In the interest of keeping nurses up to date, EONS put together a work group to consolidate much of the existing knowledge on extravasation of cancer therapies. The result of the group’s efforts is the Extravasation guidelines 2007 in the same interactive format as the previous modules.

Section 1 - What is a Guideline?

This section explains the nature of clinical guidelines, how they are established and how they can have an impact in health care.
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Section 2 - Anaemia Guidelines

This section covers the 2006 EORTC guidelines for the use of erythropoiesis stimulating proteins (ESPs) in anaemic patients with cancer, as well as other issues ESP treatment.
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Section 3 - Neutropenia Guidelines

This section covers the 2006 EORTC guidelines for the use of granulocyte-colony-stimulating factors (G-CSFs) in adult patients receiving chemotherapy for cancer, as well as other issues in the prevention and management of febrile neutropenia.
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Section 4 - Oral Mucositis Guidelines

This section covers the 2005 MASCC/ISOO for the prevention and treatment of oral mucositis in the setting of radiation therapy, chemotherapy and combined chemoradiation therapy, and also highlights strategies to be avoided in clinical practice.
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Section 5 - Implementing Guidelines

This section provides information to help overcome some of the challenges of implementing guidelines in practice, including theories and practical advice to help with implementation plans and strategies.
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Section 6 - Extravasation Guidelines 2007

This document brings together information from the available literature on the recognition, diagnosis and prevention of extravasation in cancer therapy, and highlights the management strategies for vesicant, irritant and non-vesicant extravasation, including information on the use of antidotes.
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